A new $6 billion manufacturing facility owned by Eli Lilly and Company is now coming to Huntsville. The commitment reportedly represents the largest initial investment in Alabama's history and will create approximately 3,450 manufacturing and construction jobs on-site.

According to the multinational pharmaceutical corporation, the Huntsville location will focus on domestic production of small molecule synthetic and peptide medicines, including Lilly's oral GLP-1, orforglipron.

"Huntsville's track record of science and innovation, supported by advanced manufacturing expertise and a skilled workforce, makes Alabama an ideal location for Lilly to expand domestic manufacturing capacity for next‑generation medicines," said David A. Ricks, Lilly chair and CEO. "Today's investment continues the onshoring of active pharmaceutical ingredient (API) production, strengthening supply chain resilience and reliable access to medicines for patients in the U.S."

Governor Kay Ivey praised Lilly's decision to open a facility in Huntsville, noting its historical significance to Alabama.

"Huntsville and our entire state have a proven legacy of innovation, and there is no better home for Lilly than right here in Alabama. Our roots in the biosciences industry run deep, and Alabama's contributions to this burgeoning sector continue," said Ivey. "We are proud to welcome Lilly's new U.S. manufacturing facility, which we are thrilled is the largest initial investment in our state's history."

"No doubt, Alabamians will help Lilly do things that have never been done before, and we will ensure this great company achieves their mission of improving the health and well-being of people all around the country and globe," added Ivey.

U.S. Rep. Dale Strong (R-Huntsville) called Lilly's commitment "huge news for Huntsville and American manufacturing."

U.S. Sen. Katie Britt (R-Montgomery) said the move from Lilly "underscores President Donald Trump's leadership" in driving American manufacturing to new heights.

U.S. Sen. Tommy Tuberville (R-Auburn) wrote that Huntsville is unquestionably the right place for the facility, given the city's reputation for "cutting-edge technology and state-of-the-art facilities."

Construction on the facility is expected to begin in 2026, with completion set for 2032.

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